5/5/2025
Last update
5/5/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Vitamin C (from culture of Saccharomyces cerevisiae)
60 mg
67%
Zinc (from Brown Rice Chelate)
30 mg
273%
Raw Organic Fruit & Vegetable BlendOrganic Apple (fruit), Organic Beet (root), Organic Broccoli (stalk & flower), Organic Carrot (root), Organic Spinach (leaf), Organic Tomato (fruit), Organic Strawberry (fruit), Organic Tart Cherry (fruit), Organic Blackberry (fruit), Organic Green Bell Pepper (fruit), Organic Brussels Sprout (leaf), Organic Blueberry (fruit), Organic Ginger (root), Organic Garlic (bulb), Organic Green Onion (bulb), Organic Raspberry (fruit), Organic Parsley (leaf), Organic Cauliflower (flower & stem), Organic Red Cabbage (leaf), Organic Kale (leaf), Organic Cucumber (gourd), Organic Celery (stalk), Organic Asparagus (flower & stem)
166 mg
+
Trace Mineral BlendRaw Organic Spirulina, Raw Organic Cracked-Wall Chlorella, Ancient Peat (Trace Minerals)
150 mg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU)
60 mg
+
Top Medical Research Studies
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Read More
8
We delved into the intriguing relationship between trace minerals, specifically zinc, and high cholesterol levels related to coronary artery disease (CAD). Our study focused on middle-aged and older adults living in Shika town, Japan, and involved 895 residents, carefully excluding those with a genetic predisposition to high cholesterol.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
Read More
8
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Read More
Most Useful Reviews
9
Effective zinc absorption
1 people found this helpful
In 2019, I discovered I had zinc deficiency, which resulted in hair loss and weak nails. After choosing Vitamin Code raw zinc from Garden of Life, I experienced incredible results. My zinc levels improved significantly after a month of taking two capsules daily. I believe that while higher dosages might yield quicker results, I preferred a gradual approach. Remarkably, hair loss ceased after two months, and my nails strengthened much sooner. Vitamin Code raw zinc has become a staple in my diet now for its excellent results!
Read More
9
Stomatitis relief
3 people found this helpful
Suffering from recurrent stomatitis, I took B vitamins, but they didn't prevent new ulcers. I learned that zinc deficiency might be the cause. I started taking this zinc once every two days and my mouth ulcers disappeared after a week or two. It's remarkable! Reading reviews, I found some take much higher doses of zinc, which may lead to deficiencies in copper and iron, among other issues. I believe sticking to the recommended amounts is wise, as excess can disrupt body functions. This zinc has really helped me!
Read More
7.5
Promotes immunity
5 people found this helpful
The best zinc on iHerb! This excellent, high-quality zinc in a small dosage (15 mg in one capsule) is well absorbed and doesn't cause nausea. Zinc is one of the most important micronutrients that enhances immunity during a pandemic! I’ve found it helps in recovering faster from viral diseases. I noticed that taking 3-4 capsules at the onset of a sore throat can stop the disease's progression. Personally, I’ve seen improvements in my hair, skin, and nails with this zinc. I definitely recommend this particular product as it truly stands out on iHerb!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
- All Researches
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Read More
8
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Read More
8
We delved into the intriguing relationship between trace minerals, specifically zinc, and high cholesterol levels related to coronary artery disease (CAD). Our study focused on middle-aged and older adults living in Shika town, Japan, and involved 895 residents, carefully excluding those with a genetic predisposition to high cholesterol.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
Read More
8
Study on zinc and cholesterol outcomes
We conducted a randomized clinical trial involving 75 patients with type 2 diabetes to explore the effects of a nutraceutical combination containing myo-inositol, d-chiro-inositol, α-lactalbumin, Gymnema sylvestre, and zinc on cholesterol levels.
While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.
However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.
While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.
However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.
Read More
7
Zinc's role in cholesterol management
In our study, we explored how zinc supplementation might influence cholesterol levels in a controlled experiment with male Wistar rats. We divided the 48 rats into three diet groups: those on a high-fat diet, a caloric restriction diet, and a normal diet. The high-fat diet group was further split into four categories, where some received zinc, selenium, or a combination of both, while one group served as the control.
After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.
We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.
We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective zinc absorption
1 people found this helpful
In 2019, I discovered I had zinc deficiency, which resulted in hair loss and weak nails. After choosing Vitamin Code raw zinc from Garden of Life, I experienced incredible results. My zinc levels improved significantly after a month of taking two capsules daily. I believe that while higher dosages might yield quicker results, I preferred a gradual approach. Remarkably, hair loss ceased after two months, and my nails strengthened much sooner. Vitamin Code raw zinc has become a staple in my diet now for its excellent results!
Read More
9
Stomatitis relief
3 people found this helpful
Suffering from recurrent stomatitis, I took B vitamins, but they didn't prevent new ulcers. I learned that zinc deficiency might be the cause. I started taking this zinc once every two days and my mouth ulcers disappeared after a week or two. It's remarkable! Reading reviews, I found some take much higher doses of zinc, which may lead to deficiencies in copper and iron, among other issues. I believe sticking to the recommended amounts is wise, as excess can disrupt body functions. This zinc has really helped me!
Read More
7.5
Promotes immunity
5 people found this helpful
The best zinc on iHerb! This excellent, high-quality zinc in a small dosage (15 mg in one capsule) is well absorbed and doesn't cause nausea. Zinc is one of the most important micronutrients that enhances immunity during a pandemic! I’ve found it helps in recovering faster from viral diseases. I noticed that taking 3-4 capsules at the onset of a sore throat can stop the disease's progression. Personally, I’ve seen improvements in my hair, skin, and nails with this zinc. I definitely recommend this particular product as it truly stands out on iHerb!
Read More
7.5
Natural and effective
3 people found this helpful
I’ve experienced nausea from synthetic zinc, but this Garden of Life zinc has been fantastic, as there are no adverse effects. It addresses my issues of low immunity, and I've noticed significant improvements after just one or two days of taking it. For vegetarians struggling to meet daily zinc needs, this high-quality option comes highly recommended and is definitely a repurchase for me!
Read More
Frequently Asked Questions
9
Effective zinc absorption
1 people found this helpful
In 2019, I discovered I had zinc deficiency, which resulted in hair loss and weak nails. After choosing Vitamin Code raw zinc from Garden of Life, I experienced incredible results. My zinc levels improved significantly after a month of taking two capsules daily. I believe that while higher dosages might yield quicker results, I preferred a gradual approach. Remarkably, hair loss ceased after two months, and my nails strengthened much sooner. Vitamin Code raw zinc has become a staple in my diet now for its excellent results!
9
Stomatitis relief
3 people found this helpful
Suffering from recurrent stomatitis, I took B vitamins, but they didn't prevent new ulcers. I learned that zinc deficiency might be the cause. I started taking this zinc once every two days and my mouth ulcers disappeared after a week or two. It's remarkable! Reading reviews, I found some take much higher doses of zinc, which may lead to deficiencies in copper and iron, among other issues. I believe sticking to the recommended amounts is wise, as excess can disrupt body functions. This zinc has really helped me!
7.5
Promotes immunity
5 people found this helpful
The best zinc on iHerb! This excellent, high-quality zinc in a small dosage (15 mg in one capsule) is well absorbed and doesn't cause nausea. Zinc is one of the most important micronutrients that enhances immunity during a pandemic! I’ve found it helps in recovering faster from viral diseases. I noticed that taking 3-4 capsules at the onset of a sore throat can stop the disease's progression. Personally, I’ve seen improvements in my hair, skin, and nails with this zinc. I definitely recommend this particular product as it truly stands out on iHerb!
7.5
Natural and effective
3 people found this helpful
I’ve experienced nausea from synthetic zinc, but this Garden of Life zinc has been fantastic, as there are no adverse effects. It addresses my issues of low immunity, and I've noticed significant improvements after just one or two days of taking it. For vegetarians struggling to meet daily zinc needs, this high-quality option comes highly recommended and is definitely a repurchase for me!
8
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
7
Zinc's role in cholesterol management
In our study, we explored how zinc supplementation might influence cholesterol levels in a controlled experiment with male Wistar rats. We divided the 48 rats into three diet groups: those on a high-fat diet, a caloric restriction diet, and a normal diet. The high-fat diet group was further split into four categories, where some received zinc, selenium, or a combination of both, while one group served as the control.
After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.
We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.
We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
8
Study on zinc and cholesterol outcomes
We conducted a randomized clinical trial involving 75 patients with type 2 diabetes to explore the effects of a nutraceutical combination containing myo-inositol, d-chiro-inositol, α-lactalbumin, Gymnema sylvestre, and zinc on cholesterol levels.
While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.
However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.
While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.
However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.
References
- Chhina GS, Chhabra A, Luthra SR, Khattar S, Singh P, et al. Effect of Zinc Supplementation on Glycemic Control in Newly Diagnosed Patients With Type 2 Diabetes Mellitus. Cureus. 2024;16:e69180. 10.7759/cureus.69180
- Kimura K, Suzuki F, Tsujiguchi H, Hara A, Miyagi S, et al. Relationship between coronary artery disease with dyslipidaemia and trace mineral intake: a cross-sectional analysis of the Shika study. J Nutr Sci. 2024;13:e45. 10.1017/jns.2024.26
- Hasani M, Monfared V, Aleebrahim-Dehkordi E, Jafari A, Agh F, et al. The Effect of Selenium, Zinc, and their Combined Supplementation on Cardiometabolic Biomarkers-comparing their Effects in the Energy Restriction and High-fat Diet Methods in Obese Rats. Curr Mol Med. 2024;24:1307. 10.2174/0115665240268180231113045836
- Khajeh M, Hassanizadeh S, Pourteymour Fard Tabrizi F, Hassanizadeh R, Vajdi M, et al. Effect of Zinc Supplementation on Lipid Profile and Body Composition in Patients with Type 2 Diabetes Mellitus: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis. Biol Trace Elem Res. 2024;202:4877. 10.1007/s12011-024-04059-x
- Nani A, Bertuzzi F, Meneghini E, Mion E, Pintaudi B. Combined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial. J Clin Med. 2023;12. 10.3390/jcm12247650
